26 January 2023
9.00-10.00:  Registration & Welcome coffee
10.00-10.15:  Welcome address by Prof. Dr. Ulf Nehrbass, CEO of Luxembourg Institute of Health, and the organizers
10.15-11.00:  Keynote 1: Prof. Veerle Baekelandt, KU Leuven, BE. Unraveling the role of alpha-synuclein aggregation in Parkinson’s disease and related disorders
Session 1: Cohorts and Clinical Phenotypes, Chair: Dr. Brit Mollenhauer 

11.00-11.20:  Prof. Asha Kishore, Medcity, Kochi, IN. Clinical and environmental risk factors of PD: interim observations of GAP-India

11.20-11.40:  Prof. Thomas Gasser, Hertie-Institute for Clinical Brain Research University of Tübingen, GER. Genetic risk and resilience in Parkinson’s disease

11.40-12.00:  Prof. Jean-Christophe Corvol, Paris Brain Institute, FR. The value of nation-wide patient cohorts for impact for clinical care

12.00-12.30:  Funding agencies flash presentation:
Anna Naito, Associate Vice President, Research at Parkinson’s Foundation. PD GENEration: Providing Clinical Genetic Testing and Counseling for people with PD in North America. Via Webinar
Dr. Sean Sapcariu, FNR Presentation: The Luxembourg research ecosystem and funding opportunities
12.30-13.30:  Walking lunch with exhibition and poster session

Session 2: PD Genetics and genomics, Chair: Prof. Asha Kishore 

13.30-13.50:  Prof. Enza Maria Valente, University of Pavia, IT. Understanding the mitochondrial phenotype of PD and its impact for precision medicine

13.50-14.10:  Prof. Soraya Bardien, Stellenbosch University, SA. Genetics of PD in Sub-Saharan Africa: What do we know?
14.10-14.30:  Dr. Patrick May, LCSB, University of Luxembourg, LU. Genetic risk prediction in PD

14.30-14.45: Young scientist presentation:Dr. Kanchana Soman Pillai, Aster Medicty, IN. Novel mutations in GRN, SQSTM1 and ADH1C — A case series of familial dementia with parkinsonism

Session 3: Parkinson’s disease and Cognition – from risk factors to prevention, Chair: Prof. Dr. Ullrich Wüllner 
14.45-15.05:   Prof. Pille Taba, University of Tartu, ES. Parkinson’s disease and Cognition – from risk factors to prevention

15.05-15.25:   Prof. Anja Leist, University of Luxembourg, LU. Modifiable risk factors in dementia prevention

15.25-15.45:   Prof. Andrew Singleton, National Institute of Aging, US. Dissecting PD genetics worldwide – the GP2 initiative. Via Webinar

15.45-16.00:  Young scientist presentation: Dr Sahil Mehta, PGIMER, IN. Comparison of cognitive, affective and autonomic functions in Parkinson’s                                Disease patients with and without freezing of gait and its correlation with PET/CT

16.00-16.30:   Coffee break with exhibition and poster session
Session 4: Genetic stratification for precision medicine, Chair: Prof. Dr. Thomas Klockgether

16.30-16.50:    Prof. Pramod Pal, National Institute of Mental Health and Neurosciences, IN. Impulse Control Disorders in PD

16.50-17.10:    Prof. Rupam Borgohain, Nizam’s Institute of Medical Sciences, IN. Deep Brain Stimulation in India

17.10-17.30:    Dr. Kathrin Brockmann, University Tübingen, GER. Lessons learned from GBA stratification for treatment and prediction

17.30-17.45:    Dr. Pieter-Jelle Visser, Maastricht University, NL. Molecular subtypes in Alzheimer’s disease: relevance for Parkinson’s disease

17.45-18.00:    Wrap up
18.00:     Drinks Reception
27 January 2023

8.30-8.45:     Welcome coffee
8.45-9.00:     Welcome address by Prof. Dr. Michael Heneka, Director of LCSB

9.00-9.45:     Keynote 2: Prof. Caroline Tanner, University of California San Francisco, USA. Epidemiology, Targeting Parkinson’s Disease Prevention: from Population Studies to Precision Medicine

Session 5: From cellular mechanisms to novel biomarkers, Prof. Dr. Jens Christian Schwamborn

9.45-10.05:    Dr. Brit Mollenhauer, Paracelsus-Elena Klinik, GER. Toward biomarkers for prevention trials in Parkinson’s disease

10.05-10.25:  Prof. Pankaj Seth, National Brain Research Center Manesar, IN. A primary cell culture model of human brain cells for understanding neurodegenerative diseases. Via Webinar

10.25-10.45:  Prof. Anne Grünewald, LCSB, University Luxembourg, LU. Cellular models for PD

10.45-11.00:  Young scientist presentation: Dr. Indrani Datta, National Institute of Mental Health and Neurosciences, IN. Impairment in SHH responsiveness of iPSC derived neural progenitors carrying the LRRK2 I1371V mutation contributes to the ontogenic origin of lower dopaminergic-neuron yield.
11.00-11.20:  Coffee break with exhibition and poster session
11.20-12.00:  Keynote 3: Prof. Nobutaka Hattori, Juntendo University, Japan. “Importance of Biomarkers in Sinucleinopathies and Their Applications”

Session 6: Data Management and Bioinformatics Analysis, Chair: Dr. Reinhard Schneider

12.05-12.25:  Dr. Jens Krüger, University Tübingen, GER.
12.25-12.45:  Dr. Venkata Satagopam, LCSB, University Luxembourg, LU. Developing an EU hub for at risk cohorts

12.45-13.00:  Young scientist presentation: Gianfranco Frigerio, LCSB, University Luxembourg, LU. A Methodology To Perform Accurate Systematic-Review With Meta-Analyses In Epidemiology: A Case Study for the Early-Life Exposure To Perfluoroalkyl Substances and its associations with Childhood Overweight and/or Obesity

13.00-13.30:  Funding agencies flash presentation DFG, MJFF & ICMR/DBT/DST
13.30-14.30:  Lunch